If you want a comprehensive picture of your hormonal health — not just a snapshot of a single moment, but a full 24-hour map of how your hormones are produced, metabolized, and cleared — the DUTCH test is the most advanced tool available to clinicians today.
DUTCH stands for Dried Urine Test for Comprehensive Hormones. It was developed by Precision Analytical to address the significant limitations of both blood and saliva hormone testing. By collecting four to five urine samples over the course of a day (dried onto filter paper), the DUTCH test captures the full diurnal cortisol pattern, sex hormone levels, hormone metabolites, melatonin, organic acids related to B vitamin status, and key markers of oxidative stress.
What makes the DUTCH test particularly powerful is its ability to assess how hormones are being metabolized — not just what the levels are. For example, you can have a “normal” estradiol level but be converting it predominantly through the 16-hydroxy pathway, which is associated with increased breast tissue proliferation, rather than the protective 2-hydroxy pathway. This distinction is invisible on a blood panel but clearly visible on the DUTCH.
The DUTCH also provides the most complete picture of adrenal function available outside of a full endocrinology workup. The cortisol awakening response, free cortisol curve throughout the day, and total cortisol production — along with the metabolized cortisol values — reveal patterns of HPA axis dysregulation that a single morning serum cortisol completely misses.
For women on hormone therapy, the DUTCH is particularly valuable for monitoring metabolite pathways and ensuring estrogen is being processed safely. For men on testosterone, it reveals aromatase activity and DHT conversion rates.
We use the DUTCH test as a cornerstone of our comprehensive hormonal evaluation. Call 844-734-2112 or contact us to get started.